Virtual Journal Club 6: HPB

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Though slow, progress is being made worldwide against pancreatic cancer. Advances in imaging, staging, resection, and palliation are being realized and are helping more and more patients. New outcome metrics are being refined to reflect and drive overall quality of care. This occurs in parallel to technical advances for pancreatectomy. While a breakthrough systemic therapy is still awaited, new and aggressive chemotherapy, radiation therapy and soon biotherapy regimens are being advanced. These recently published HPB articles together with an expert procedure video provide your Journal Club the content to meet these Learning Objectives:

Using a review of 66 literature articles, understand the roles of contemporary imaging modalities in the diagnosis and determination of resectability of pancreatic cancer.
Understand the purpose and value of pancreatic cancer clinical care guidelines, and how non-compliance and variations in care can undermine quality and patients outcomes.
Understand whether contemporary imaging and staging modalities of pancreatic head cancers can accurately predict the need and extent of vascular resection during open pancreaticoduodenectomy.
Understand the challenges and technical feasibility of major venous resection during total laparoscopic pancreaticoduodenectomy.
Understand the utility, options and outcomes for various operative and non-operative palliation measures for unresectable pancreatic cancer.
Review an expert opinion of why deliberate multimodal therapy of cancer cachexia will be essential in our next era of pancreatic cancer care.

Multimodality imaging of pancreatic ductal adenocarcinoma: a review of the literature

Shailesh V. Shrikhande, Savio George Barreto, Mahesh Goel, Supreeta Arya

DOI: https://doi.org/10.1111/j.1477-2574.2012.00508.x

HPB, Vol. 14, Issue 10, p658–668

Open Archive

Failure to comply with NCCN guidelines for the management of pancreatic cancer compromises outcomes

Brendan C. Visser, Yifei Ma, Yulia Zak, George A. Poultsides, Jeffrey A. Norton, Kim F. Rhoads

DOI: https://doi.org/10.1111/j.1477-2574.2012.00496.x

HPB, Vol. 14, Issue 8, p539–547

Open Archive

Highlights in this issue

Saxon Connor, Stephen Wigmore, Mark Callery

DOI: https://doi.org/10.1111/hpb.12167

HPB, Vol. 15, Issue 8, ii

Open Archive

Radiologic and intraoperative detection of need for mesenteric vein resection in patients with adenocarcinoma of the head of the pancreas

Matthew R. Porembka, William G. Hawkins, David C. Linehan, Feng Gao, Changqing Ma, Elizabeth M. Brunt, Steven M. Strasberg

DOI: https://doi.org/10.1111/j.1477-2574.2011.00343.x

HPB, Vol. 13, Issue 9, p633–642

Open Archive

Major venous resection during total laparoscopic pancreaticoduodenectomy

Michael L. Kendrick, Guido M. Sclabas

DOI: https://doi.org/10.1111/j.1477-2574.2011.00323.x

HPB, Vol. 13, Issue 7, p454–458

Open Archive

Operative procedures for unresectable pancreatic cancer: does operative bypass decrease requirements for postoperative procedures and in-hospital days?

John M. Lyons, Ami Karkar, Camilo C. Correa-Gallego, Michael I. D'Angelica, Ronald P. DeMatteo, Yuman Fong, T. Peter Kingham, William R. Jarnagin, Murray F. Brennan, Peter J. Allen

DOI: https://doi.org/10.1111/j.1477-2574.2012.00477.x

HPB, Vol. 14, Issue 7, p469–475

Open Archive

Cachexia in pancreatic cancer: new treatment options and measures of success

Kenneth C.H. Fearon, Vickie E. Baracos

DOI: https://doi.org/10.1111/j.1477-2574.2010.00178.x

HPB, Vol. 12, Issue 5, p323–324

Open Archive

HPB Virtual Journal Club Number 6, October 2013

“Making Progress Against Pancreatic Cancer”

Multimodality imaging of pancreatic ductal adenocarcinoma: a review of the literature

Failure to comply with NCCN guidelines for the management of pancreatic cancer compromises outcomes

Highlights in this issue

Radiologic and intraoperative detection of need for mesenteric vein resection in patients with adenocarcinoma of the head of the pancreas

Major venous resection during total laparoscopic pancreaticoduodenectomy

Operative procedures for unresectable pancreatic cancer: does operative bypass decrease requirements for postoperative procedures and in-hospital days?

Cachexia in pancreatic cancer: new treatment options and measures of success