HPB Virtual Journal Club Number 5, August 2013

"Improving long term outcomes in hepatocellular carcinoma (HCC)"

Hepatocellular carcinoma is a global health problem which occurs in patients from countries with high incidence of viral hepatitis but also in patients with other kinds of liver disease.

There are many available treatment options for patients with HCC but choosing the one likely to give the best outcome and in the context of sometimes limited resource can be difficult. These recently published HPB articles provide your Journal Club the content to meet the Learning Objectives below.

At the conclusion of this journal club, participants will be able to:

  • Delineate the role and success of prospective screening for patients at high risk for the development of HCC, and outline the impact of screening with respect to identification of patients with potentially curable disease.
  • Define the appropriate management strategy for patients with multiple tumors, including consideration of tumors exhibiting different behaviors.
  • Delineate how viral status impacts outcome following liver transplantation for HCC.
  • Define how treatment of underlying viral disease is advantageous if treatment can be tolerated in terms of long-term survival and likelihood of recurrence.
  • Describe the potential impact that obesity may pose for recurrence of HCC in patients undergoing liver transplant.