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Efficiency of percutaneous transhepatic cholangioscopy in the treatment of biliary complications after liver transplantation

  • Author Footnotes
    1 Aimaiti Yasen and Jun Feng contributed equally to this work and shared the first authorship.
    Aimaiti Yasen
    Footnotes
    1 Aimaiti Yasen and Jun Feng contributed equally to this work and shared the first authorship.
    Affiliations
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
    Search for articles by this author
  • Author Footnotes
    1 Aimaiti Yasen and Jun Feng contributed equally to this work and shared the first authorship.
    Jun Feng
    Footnotes
    1 Aimaiti Yasen and Jun Feng contributed equally to this work and shared the first authorship.
    Affiliations
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
    Search for articles by this author
  • Run-Bin Liang
    Affiliations
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
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  • Can-Hua Zhu
    Affiliations
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
    Search for articles by this author
  • Jun Li
    Affiliations
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
    Search for articles by this author
  • An-Zhong Liu
    Affiliations
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
    Search for articles by this author
  • Yan-min Liu
    Affiliations
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
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  • Guo-Ying Wang
    Correspondence
    Corresponding author. , Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, No. 151 Yanjiang Road, Guangzhou 510120, Guangdong Province, China, Tel.: +8613632407313; fax: +20 83062923.
    Affiliations
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, Guangdong Province, China
    Search for articles by this author
  • Author Footnotes
    1 Aimaiti Yasen and Jun Feng contributed equally to this work and shared the first authorship.
Published:January 24, 2023DOI:https://doi.org/10.1016/j.hpb.2023.01.010

      Abstract

      Background

      Percutaneous transhepatic cholangioscopy (PTCS) has provided an alternative therapeutic option for handling refractory biliary complications in liver transplanted recipients. This study aimed to evaluate short-term PTCS efficiency in the management of biliary complications following liver transplantation.

      Methods

      Clinical data of 25 patients who received therapeutic PTCS due to biliary complications after liver transplantation were retrospectively analyzed.

      Results

      Therapeutic PTCS was successfully performed in 25 patients. Biliary complications were anastomotic strictures in seven cases, intrahepatic cholangiolithiasis in four cases, extra-and intrahepatic cholangiolithiasis in three cases, choledocholithiasis complicated with anastomotic strictures in four cases, intrahepatic cholangiolithiasis complicated with non-anastomotic strictures in one case, intrahepatic cholangiolithiasis complicated with anastomotic strictures in five cases, intrahepatic cholangiolithiasis complicated with anastomotic strictures and ischemic cholangitis in one case. The median time between liver transplantation and first PTCS was 24 months, and the median times of PTCS was 2.6. Clinical manifestations were significantly improved in most patients after PTCS, and biliary complications were successfully managed through PTCS in 15 cases, which were partially effective in eight cases and ineffective in two cases. PTCS was more effective in tackling anastomotic strictures and cholangiolithiasis.

      Conclusion

      PTCS was an effective therapeutic modality for treating refractory biliary complications following liver transplantation.

      Keywords

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