We read with great interest the recently published article “Liver Resection and role
of Extended Histology (LiREcH study) in patients with multifocal colorectal cancer
liver metastases” by Hassan et al.
1
The authors have shown that the margin status was not related to the outcomes in
patients with colorectal liver metastases. We support the use of non-anatomical resection
(parenchyma-preserving hepatectomy) in patients with multifocal CRLM, by either laparoscopic
or open surgery.
2
,3
Anatomic liver resection has the potential to reduce postoperative recurrence. This
study only demonstrated that margin status does not affect local recurrence, however,
the authors were not able to conclude whether recurrence was reduced in some patients
in who it was possible to remove all tumors by hemihepatectomies, extended hemihepatectomies
and associated liver partition and portal vein ligation for staged hepatectomy (ALPPS).
4
Therefore, we believe that the choice of surgical approach remains a matter of serious
discussion for patients in whom all lesions can be removed by major hepatectomy.To read this article in full you will need to make a payment
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References
- Liver Resection and role of Extended Histology (LiREcH study) in patients with multifocal colorectal cancer liver metastases.HPB. 2021; 23: 1615-1622
- Laparoscopic surgery for colorectal liver metastases: moving forward while keeping feet on the ground.Hepatobiliary Surg Nutr. 2021; 10: 107-109
- Addressing the variation in hepatic surgery for colorectal liver metastasis.Hepatobiliary Surg Nutr. 2021; 10: 103-106
- Current status of treatment for colorectal liver metastases in the United Kingdom.Hepatobiliary Surg Nutr. 2021; 10: 116-118
Article info
Publication history
Published online: July 15, 2022
Accepted:
June 28,
2022
Received in revised form:
June 21,
2022
Received:
June 12,
2022
Publication stage
In Press Uncorrected ProofIdentification
Copyright
© 2022 Published by Elsevier Ltd on behalf of International Hepato-Pancreato-Biliary Association Inc.